I'm currently taking 900mg SJW everyday + 25mg 5-HTP every 2 days, this com!


Question: I'm currently taking 900mg SJW everyday + 25mg 5-HTP every 2 days, this combo is working great for me.?
But the 5-htp is causing me really bad stomach pains,

Is there any other supplement out there without these effects but have the same mood boosting feeling?

The St Johns wort I take has no side effects at all, and it really helps my anxiety.

Tom

Answers:

Best Answer - Chosen by Voters

I find it unlikely the 5-htp is causing the stomach pains.

Your only risk combining the two is minimal and unlikely given the dosages you are taking. If you took like 300mg+ of 5-htp on top of the SJW you could get Serotonin syndrome.
It sounds scary but at your dosage, its highly unlikely.

Another way of administering 5-htp is to rub it into your gums or let it disolve under your tounge. Id use a smaller amount that way. Maybe 10mg.

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Serotonin syndrome is a potentially life-threatening adverse drug reaction that may occur following therapeutic drug use, inadvertent interactions between drugs, overdose of particular drugs, or the recreational use of certain drugs. Serotonin syndrome is not an idiosyncratic drug reaction; it is a predictable consequence of excess serotonin activity at central nervous system (CNS) and peripheral serotonin receptors.[1] For this reason, some experts strongly prefer the terms serotonin toxicity or serotonin toxidrome because these more accurately reflect the fact that it is a form of poisoning.[2][3] It may also be called serotonin storm, hyperserotonemia, or serotonergic syndrome.

The excess serotonin activity produces a spectrum of specific symptoms including cognitive, autonomic, and somatic effects. The symptoms may range from barely perceptible to fatal.[1] Numerous drugs and drug combinations have been reported to produce serotonin syndrome. Diagnosis of serotonin syndrome includes observing the symptoms produced and a thorough investigation of the patient's history. The syndrome has a characteristic picture but can be mistaken for other illnesses in some patients, particularly those with neuroleptic malignant syndrome. No laboratory tests can currently confirm the diagnosis.[3]

Treatment consists of discontinuing medications which may contribute and in moderate to severe cases administering a serotonin antagonist. An important adjunct treatment includes controlling agitation with benzodiazepine sedation. The high profile case of Libby Zion, who is generally accepted to have died from serotonin syndrome,[1] resulted in changes to graduate medical education in New York State.[4]




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