Guaifenesin!!!!! A few questions!?!


Question:

Guaifenesin!!!!! A few questions!?

Ok, so I hear Guaifenesin is a muscle relaxer at higher doses is this true? I have puked many times at lower doses but ones at 1000 and up I feel numb, and I heard it is being used to treat a disorder. But Im just wondering is it'? and for all the people who come here and ***** about not doing drugs and stuff, Take your opnions somewere else!

Additional Details

2 weeks ago
Yea, I use to take the cough medicines and puke all the time when i had about 300 to 500 mgs,...But dam at 2000 it wasnt bad, just wonder what the side effects are. I heard you cant OD on it!!

2 weeks ago
How long of a paralized state?! Like forever or like a heroin high?


Answers:

It is being suggested as a treatment for fibromyalgia, and yes it does act as a skeletal muscle relaxant, but I don't know how high a dose would have that effect. Although, in high enough doses it can induce paralysis.
Whatever blows your hair back, dude.
June 30 P.S.: The paralysis is reported to be temporary in that website I quoted. Here is a particularly juicy excerpt:

"It has been found that all of these propanediol derivatives act as central-acting skeletal muscle relaxants by selectively depressing transmission of nerve impulses at the internuncial neurons of the spinal cord, brainstem, and subcortical regions of the brain. At low doses they act to relax hypertonic muscles and to lower response to sensory stimuli, i.e. pain. Thus, they might be very useful for people with fibromyalgia. At high enough of a dose, they can cause temporary muscle paralysis. This is all explained on the following web page:

http://www.vedco.com/products/productpag...

To achieve muscle paralysis, the recommended dose for large animals is 50mg per pound. Assuming a similar dose rate for humans, for a person weighing 100 pounds, the recommended dose would be 5000mg. Of course, this amount is meant for extreme relaxation to allow for surgery. A muscle relaxant effect would still be seen at much lower doses. Patients on guaifenesin for fibromyalgia take anywhere from 600 to 3600mg per day. Dr. St. Amand's own wife takes as much as 4800mg per day. So this effect would likely be significant in these people.

Additionally, in the previously mentioned study that compared Robaxin and guaifenesin, it was found that the two drugs had comparable muscle relaxant effects at similar dose levels. Since the maintenance dose for Robaxin is 1500mg, we can infer that the same level dose of guaifenesin would also have significant relaxant effects. And in fact, many people with who take guaifenesin, take a dose that is close to that amount."
I hope you find this info helpful for your, um, recreational pursuits. I have found the topic quite interesting actually, so thank you for the question. My mom thinks she has fibromyalgia so I will be reading more about guaifenesin.




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