Januvia tab 100mg, 1 tablet once a day. what is it and what is it for?!
Question:
Januvia tab 100mg, 1 tablet once a day. what is it and what is it for?
Answers:
Januvia is an orally-active inhibitor of the dipeptidyl peptidase-4 (DPP-4) enzyme. The DPP-4 enzyme inactivates incretin hormones, which are involved in the physiologic regulation of glucose homeostasis. By inhibiting DPP-4, Januvia increases and prolongs active incretin levels. This in turn increases insulin release and decreases glucagon levels in the circulation in a glucose-dependent manner.
Januvia is specifically indicated for the improvement of glycemic control in patients with type II diabetes mellitus as monotherapy or combination therapy with metformin or a peroxisome proliferatoractivated receptor gamma (PPAR) agonist (e.g., thiazolidinediones) when the single agent does not provide adequate glycemic control.
Januvia is supplied as 25 mg, 50 mg or 100 mg tablets designed for oral administration. The recommended initial dose of the drug is 100 mg once daily.