Can anti depressant cause permanante sexual side effects?!


Question: Can anti depressant cause permanante sexual side effects!?
even after coming off of themWww@Answer-Health@Com


Answers:
It has long been known that SSRIs sometimes cause permanent neurological damage to the pathway of physical sexual pleasure!. It has not been understood exactly why this happens, except that it likely involves chronic depletion of serotonin from certain serotoninergic neurons, and consequent damage to said neurons!. Ultimately, that must somehow reduce the binding of dopamine to D1 receptors (which is what causes pleasure)!. Due to PSSD's relation to serotonin depletion, the people that are most prone to PSSD are those that have genetic alleles that cause weak serotoninergic function!.

The striatum is rich in dopamine and D1 receptors, is adjacent to the nucleus accumbens (the primary pleasure center), and is involved in movement control (and is therefore lacking dopamine in the case of Parkinson's disease)!.

The striatum is also largely responsible for sexual pleasure!. Furthermore, it's sex-related function is dependent upon input from serotoninergic neurons!. PSSD can be the result of damage to these serotoninergic neurons in the striatum, and consequent lack of dopamine release to the sex-related neurons of the striatum, and in turn, the lack of sex-related pleasure in the nucleus accumbens!. The fact that there is a direct effect upon the striatum, and only an indirect effect upon the nucleus accumbens, also explains why sexual pleasure is effected by PSSD, whereas other types of pleasure (such as that of food) remain intact!.



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SSRI medications -can- do this, but there have been a grand total of seven cases reported in the past 20-25 years of SSRI use!. There's never been a reported case with tricyclic antidepressants or MAOI type, same goes for multiple reuptake inhibitors like Effexor, Wellbutrin or Cymbalta!.

This is!.!.!. astronomically rare!. This is rarer than the side effect of ibuprofen which causes skin to detach from the flesh underneath!. This is not something you, or anyone you ever meet will have to worry about!. I suspect there's something genetically special about these people, some ultra-rare abnormality in how the brain or serotonin system is wired - but again!. This is so rare we can't even really study exactly what happens!. There simply aren't enough people!.

Essentially, the answer is almost no!. Everyone regains function within a month or two of stopping the drug!.Www@Answer-Health@Com

it is not permanent, It is just a short term!. When you stop the medication!. the effect will leave!. Don't worry and other factor could contribute to sexual effect!. Www@Answer-Health@Com

No, not permanent!. Once you're off the medication your libido should return to normal!. If it doesn't, you should maybe go back to your Dr!.Www@Answer-Health@Com

it could cause nervous weekness and sweating!.!.!.

it could definitely lead to an impact on ur sex life(Adverse)Www@Answer-Health@Com

it can cause temprarly delayed ejaculationWww@Answer-Health@Com

no pernamntnyWww@Answer-Health@Com

no, but it may take a while to get them out of your systemWww@Answer-Health@Com





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