Trying to figure out if Effexor RX 37.5 is equivalent to Zoloft 100 mg?!
Question: Trying to figure out if Effexor RX 37!.5 is equivalent to Zoloft 100 mg!?
Have a friend currently on Zoloft 100mg, wanting to get off because they're not working for him, he still feels like blah, unmotivated, still sad!. I was on effexor RX for a couple months and they worked great for me and he now wants to try but wanted to know if the 37!.5 effexor equivalent to 100mg of zoloft!?Www@Answer-Health@Com
Answers:
There can be no comparison made between these two drugs!. Both drugs work on the same principle, however, in that they block the re-uptake of neurotransmitters in your brain!.
Serotonin, dopamine, and norepinephrine are the 3 involved!. These molecules have a profound effect on your mood!. They normally travel from one neuron in the brain to the next en route to achieving their effect!. These drugs intervene in the process!.
Serotonin, along with the others, is released from a neuron into a space called the synapse!. It needs to get to the adjacent cell so the message can be relayed to the next neuron, etc!. This is achieved by utilization of serotonin receptors!. Receptors are located on the adjacent cell and when the serotonin bumps into one, the cell responds and the process continues!.
In addition, there are receptors located on the cell that originally released the serotonin!. This is a recycling mechanism; the serotonin is taken back in to be used again!. Enter Zoloft!. Zoloft binds to these re-uptake sites on the neuron, which results in increased levels of serotonin in the synapse, which makes propagation of the signal much more likely and your mood is elevated!. Zoloft also works minimally on norepinephrine and dopamine re-uptake sites!.
Effexor is basically the same, but it is better at blocking norepinephrine than Zoloft!. The problem arises when the patient's body adjusts due to prolonged exposure to the drug!. Your body is very efficient, and in response to increased levels of serotonin in the synapse, the brain decreases the amount of receptor sites available on the adjacent neuron and increases the amount of re-uptake sites on the releasing neuron!.
While these drugs may seem identical, each person is affected differently!. (Patient A may have less sites that the drug has to bind to, so a smaller dose is more effective!. Another patient may not be able to metabolize a certain drug efficiently, but has no problem with a different drug!.) The only way of knowing what works is trial and error!. Www@Answer-Health@Com
Serotonin, dopamine, and norepinephrine are the 3 involved!. These molecules have a profound effect on your mood!. They normally travel from one neuron in the brain to the next en route to achieving their effect!. These drugs intervene in the process!.
Serotonin, along with the others, is released from a neuron into a space called the synapse!. It needs to get to the adjacent cell so the message can be relayed to the next neuron, etc!. This is achieved by utilization of serotonin receptors!. Receptors are located on the adjacent cell and when the serotonin bumps into one, the cell responds and the process continues!.
In addition, there are receptors located on the cell that originally released the serotonin!. This is a recycling mechanism; the serotonin is taken back in to be used again!. Enter Zoloft!. Zoloft binds to these re-uptake sites on the neuron, which results in increased levels of serotonin in the synapse, which makes propagation of the signal much more likely and your mood is elevated!. Zoloft also works minimally on norepinephrine and dopamine re-uptake sites!.
Effexor is basically the same, but it is better at blocking norepinephrine than Zoloft!. The problem arises when the patient's body adjusts due to prolonged exposure to the drug!. Your body is very efficient, and in response to increased levels of serotonin in the synapse, the brain decreases the amount of receptor sites available on the adjacent neuron and increases the amount of re-uptake sites on the releasing neuron!.
While these drugs may seem identical, each person is affected differently!. (Patient A may have less sites that the drug has to bind to, so a smaller dose is more effective!. Another patient may not be able to metabolize a certain drug efficiently, but has no problem with a different drug!.) The only way of knowing what works is trial and error!. Www@Answer-Health@Com
There isn't an equivalent between these drugs because they are not the same!. Zoloft works on serotonin and effexor works on serotonin and norepinephrine!. Can't compare them!. Go to a doctor and get their opinion on what to do!.Www@Answer-Health@Com