What in the brain causes depression?!


Question:

What in the brain causes depression?


Answers:

depression is a chemical imbalance in the brain this is the result of thoughts or emotions that were troubling for a person. Some factors can also be triggered The three most important of these are biological, genetic, and environmental factors. Genetic Factors
Scientists believe genetic factors play a role in some depressions. Researchers are hopeful, for instance, that they are closing in on genetic markers for susceptibility to manic-depressive disorder.

Recent genetic research also supports earlier studies reporting family links in depression. For example, if one identical twin suffers from depression or manic-depressive disorder, the other twin has a 70 percent chance of also having the illness. Other studies that looked at the rate of depression among adopted children supported this finding. Depressive illnesses among adoptive family members had little effect on a child's risk of depression; however, the disorder was three times more common among adopted children whose biological relatives suffered depression.

Biological Causes
Additional research data indicate that people suffering from depression have imbalances of neurotransmitters, natural substances that allow brain cells to communicate with one another. Two transmitters implicated in depression are serotonin and norepinephrine. Scientists think a deficiency in serotonin may cause the sleep problems, irritability, and anxiety associated with depression. Likewise, a decreased amount of norepinephrine, which regulates alertness and arousal, may contribute to the fatigue and depressed mood of the illness.Other body chemicals also may be altered in depressed people. Among them is cortisol, a hormone that the body produces in response to stress, anger, or fear. In normal people the level of cortisol in the bloodstream peaks in the morning, then decreases as the day progresses. In depressed people, however, cortisol peaks earlier in the morning and does not level off or decrease in the afternoon or evening.

Researchers don't know if these imbalances cause the disease or if the illness gives rise to the imbalances. They do know that cortisol levels will increase in anyone who must live with long-term stress.

Environmental Situations
Certain environmental situations, such as stress or breakup of important attachments, also may precipitate depression, especially in vulnerable persons.




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