What specific defect is responsible for Hodgkin lymphoma?!
Question: What gene is affected and how does this alter the regulation of the cell cycle or cell number?
Answers: What gene is affected and how does this alter the regulation of the cell cycle or cell number?
As a survivor of Non-Hodgkin's Lymphoma, I think I can answer your question. There is in your DNA a bunch of links. They are numbered some way. Let us say for argument that 4 is supposed to be connected to 8. In lymphoma 4 might be connected to 5. The scientists are working on a gene therapy for curing the broken link that causes the lymphoma. The problems besides the cost of the treatment when they are ready to try it, include the fact that the treatment is only good for one person. Each person with lymphoma would have to get a special treatment, thereby driving the cost up even higher. But there is hope. If they can figure out how to do this, they will be able to figure out how to do it in mass and lower the costs significantly.
Here is where you'll find the best info:
http://www.leukemia-lymphoma.org/hm_lls
Best wishes