How would the kidney respond to an injury that caused severe blood loss?!


Question: A. the afferent arterioles would constrict, the efferent arterioles would dilate.

B. both the afferent and efferent arterioles would constrict.

C. blood loss does not alter kidney function.


Answers: A. the afferent arterioles would constrict, the efferent arterioles would dilate.

B. both the afferent and efferent arterioles would constrict.

C. blood loss does not alter kidney function.

I am not sure about my answer but I tried to conclude it from reading from differnt sources:

If you lose a lot of blood, the amount of iron and red blood cells in your body decreases so it will be harder for the bone marrow to "rebuild blood cells"
The bone marrow also needs a stimulus to make blood. That stimulus is the hormone erythropoietin (you may here us call it EPO in the clinics). Erythropoietin is primarily made by the kidney in response to anemia and tells the bone marrow when to make blood. When the kidneys begin to fail, they make less and less erythropoietin and the patient then develops anemia.

So you can say as a response the kidney makes more Erythropoitin. This requires the efferent arterioles (the one that controls blood outflow) to constrict (to stop blood outflow==bleeding). However at the same time, the affernt arterioles would also contrict to prevent the blood inflow and decrease the blood pressure (blood pressure will later cause more bleeding).
This was a conclusion based of facts taken from those two websites, but not a certain answer:
http://www.kidney-hypertension.com/anemi...
http://www.nature.com/ki/journal/v59/n1/...

I would say the answer is "B"
Good luck B

Salaam

blood loss that causes shock can damage the kidneys and can lead to acute renal failure.





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