Type 1 diabetes and Vitiligo.?!
Question: My husband has type 1 dieabets....he was diagnosed at age 26. He also has vitaligo....diagnosed at age 16. I'm very concerned that our children are going to end up with his autoimmunie gene. Does anyoen know the odds that my son will end up with either of these?
Answers: My husband has type 1 dieabets....he was diagnosed at age 26. He also has vitaligo....diagnosed at age 16. I'm very concerned that our children are going to end up with his autoimmunie gene. Does anyoen know the odds that my son will end up with either of these?
Here is a good article for you to read on how Type I diabetes can be inherieted and it's likely hood.
http://abcnews.go.com/Health/DiabetesRis...
Here is one for Veraligo:
http://www.dermabest.com/Vitiligo_inheri...
I hope these help you.
Diabetes Mellitus is a group of metabolic diseases that share the phenotype of hyperglycemia. The metabolic deregulations associated with diabetes causes secondary pathophysiological changes in multiple organ systems including the skin. Diabetes mellitus is associated with many skin diseases one of which is vitiligo.
Vitiligo is an acquired idiopathic disorder of melanogenesis characterized by depigmented macules in an otherwise normal skin. Why does vitiligo develop in diabetes? What is responsible for the depigmentation of vitiligo in diabetes? Sezary and Dupuy were the first to mention the association between diabetes and vitiligo and they attributed the skin discoloration to some pancreatic influence. Since that time, many cases of diabetes with vitiligo has been documented.
Both diabetes and vitiligo share a common theory of autoimmunity
The occurrence of depigmentation of vitiligo is certain but the etiopathogenesis remains an enigma. Vitiligo and diabetes may have a causal relationship and both are associated with autoimmunity.
Familial-hereditary tendencies occur in both diseases. There is neuropathic complications in diabetes and in vitiligo dermatodermal variety occur with evidence of degenerated nerve endings. Multiple pathogenetic mechanisms may be involved. Vascular and non-vascular pathogenetic mechanisms play a role in diabetic complications. The products of oxidative stress, free radical generation and release of various growth factors may be cytotoxic affecting melanogenesis
For more info on diabetes related issues visit
http://www.reddiabetes.com