My mom has xanthelasma?!


Question: I've been trying to find out what could be causeing it and have found a few things. I found out that diabetes, which is negative, Primary Biliary Cirrosis, which we arent sure yet- she's going to go to her doctor AGAIN:{, high cholesterol, which is negative, and some cancers cause ther xanthelasmas. The information I have been unable to find is WHAT cancers cause this? She hasd been to her doctor and several other a hundred times. I hate to say it but they don't seem to know their a** from a hole in the ground. Most of the information we do know we found for ourselves online. She's had these xanthomas on her eyelids for years. We just want to find out what could be cuasing it. She wants them off of her eyes and I dont want her to die, she's only 42:( Does anyone know what cancers could be causeing this? I know that it can be caused be metabolic disorders. Thank you for reading so much and for trying to help.


Answers: I've been trying to find out what could be causeing it and have found a few things. I found out that diabetes, which is negative, Primary Biliary Cirrosis, which we arent sure yet- she's going to go to her doctor AGAIN:{, high cholesterol, which is negative, and some cancers cause ther xanthelasmas. The information I have been unable to find is WHAT cancers cause this? She hasd been to her doctor and several other a hundred times. I hate to say it but they don't seem to know their a** from a hole in the ground. Most of the information we do know we found for ourselves online. She's had these xanthomas on her eyelids for years. We just want to find out what could be cuasing it. She wants them off of her eyes and I dont want her to die, she's only 42:( Does anyone know what cancers could be causeing this? I know that it can be caused be metabolic disorders. Thank you for reading so much and for trying to help.

First let me help you to understand what xanthelasma is exactly. Xanthelasma are yellowish plaques that usually present near the inner portion of the eyelid (closest to the nose). It tends to favour the upper lip more so than the lower lid. This is a very very common cutaneous xanthoma in those with preexisting factors.

Half of all of these lesions occur in people who have elevated plasma lipid levels. Others occur due to different lipoprotein compositions or structure for instance with low levels of HDL. Often people with Type II and IV hyperlipidemia. There is also some evidence of primary genetic cause where it tends to run in certain families. Presentation usually occurs within the 4th and 5th decade in life and there is an increased in presentation in women compared to men.

These lesions have no malignant potential however there are some differential diagnoses that your physician should always keep in mind. These differentials are normally associated with people with immunocompromised systems but since you asked specifically I will tell you the malignancies that are associated with the lids, they are carcinoma, sarcoma, and melanoma. I would like to stress that these are very rarely mistaken for xanthelasmas or anything other than malignancies. There are even more rare malignancies but as previously mentioned that are often associated with immune suppression.

Due to the fact that many of the people who have this also have lipid disorders, plasma lipids levels are essential in addition to LDL and HDL cholesterol levels. If there is any suspicion on behalf of the physician that this could be a more serious condition mimicking xanthelasma he/she will do a pathological analysis following surgical excision.

Contrary to a previous poster dietary restriction and reduction of serum lipids have only limited response in overall treatment. The most common recourse is surgical excision, although laser ablation, cauterization, electrodesiccation and cryotherapy are also options. Recurrence is common (~40%) especially if it is a secondary excision. Recurrence normally occurs within one year of treatment.

The cause;- It is excess FAT yellow in color. Tumors form on eyelids & skin.
If she STOPS eating food containing CAROTENE , she will recover.

True xanthelasma is not cancer and has no pre-malignant potential. Read the attached article and try not to worry so much.





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