TB in the lungs, what are the implications of being Rifadin resistant?!
Question: Younger brother seriously ill now, lungs getting worse, appears to be resistant to the medication and the doctors are close to useless!
Any ideas because my mother thinks he's going to die?
Answers: Younger brother seriously ill now, lungs getting worse, appears to be resistant to the medication and the doctors are close to useless!
Any ideas because my mother thinks he's going to die?
My heart goes out to you and your family and you must all be worried sick.
There are two main drugs used to treat TB Rifampiclin and Isonizid and it sounds like he has built up a resistance to the one drug which unfortunatly happens with TB.
It is difficult to treat when this happens and the doctors must be wondering what to do next for the best as this illness is hard to deal with and control.
I do not know much about it as I did not come in to contact with it very much but do know that it can take 6 to 12 months for treatment to start showing an improvement. It sounds as if he has Mycobacteruim tuberculosis as he is in secondary stages of resistance. I am not sure what will happen but not going to lie and he is very sick indeed.
Have they had to test you all as i would imagine they would as you have all come in to contact with him and they will test and treat you all if needed?
My thought are with you all and so sorry I could not be of anymore help I know it is a long hall with TB and can take months to get over.
http://www.drugs.com/cons/rifadin.html
This article MAY answer some of your questions.
I sincerely hope that your family get well soon
I am sorry to hear that. His MD should know that in the present consensus on the treatment of tuberculosis, the world health organization recommends the use of a four-drug regimen: Rifampicin, Isoniazid, Pyrazinamide and Ethambutol. This is the first line drugs used for tuberculosis as Mycobacterium tuberculosis has developed resistance to most antibiotics due to inappropriate treatment plan and misuse of antibiotics. NOw, if your brother is resistant to rifampicin, it should be withdrawn and streptomycin is added to the regimen. Streptomycin will be given via injection while the other drugs are to be taken orally. He also has to be monitored for increase in his liver enzymes (SGPT/SGOT) as the drugs are metabolized in the liver. I am certain with the use of recommended medication of the world health organization, your brother will be back in no time to his pink of health. Also, since your brother has become resistant to rifampicin, he will be on the drug regimen for at least a year. But with proper medication, one year will just be a short time!
The resistant type of TB has to be treated with a few different antibiotics at the same time. This works out fine and your brother should be ok.
I don't have an answer M but will continue to send you all, and especially your brother, the healing you all need. My heart goes out to you all bless you.