Vinblastine drugs that assemble microtubule?!


Question: Vinblastine is a drug that interferes with the assembly if microtubules. It is widely used for chemotheraphyin treating cancer patients. Suggest a hypothesis to explain how vinblastine slows tumour growth by inhibiting cell division.

thank you 5 star to anyone who can assist me!!


Answers: Vinblastine is a drug that interferes with the assembly if microtubules. It is widely used for chemotheraphyin treating cancer patients. Suggest a hypothesis to explain how vinblastine slows tumour growth by inhibiting cell division.

thank you 5 star to anyone who can assist me!!

Microtubules are very important during cell division. If the assembly is disrupted, the cell can not go past metaphase. The microtubules help the chromosomes line up during metaphase. If this phase is interrupted the cell can not finish division. Since cancer cells are cells that basically proliferate nonstop, the interruption of the microtubules will stop the cancer cells from proliferating.

Hope that helps a little.





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