Can you expalin to me what macrocytosis is all about?!


Question: Can you expalin to me what macrocytosis is all about!?
Is it dangerous!? The Dr thinks my husband has it!. I do know it has something to do with his kidneys!. But that's all I know!.
I've tried looking it up on the web but the language is way over my head!. So could someone please explain it in laymans terms!?Www@Answer-Health@Com


Answers:
Macrocytosis is the enlargement of red blood cells with near-constant haemoglobin concentration, and is defined by a mean corpuscular volume (MCV) of greater than 100 femtolitres (the precise criterion varies between laboratories)!.
this means larger than normal red blood cells

[edit] Causes
Most commonly (especially when the increase in size is mild, and just above normal range) the etiology is bone marrow dysplasia primary to alcohol abuse!. Other causes may include:

Megaloblastosis (Vitamin B12 or folate deficiency; or DNA synthesis-inbiting drugs)
hypothyroidism
reticulocytosis (commonly from hemolysis or a recent history of blood loss)!.
liver disease
myeloproliferative disease

[edit] Complications
No complications arise from macrocytosis itself and a prognosis will be determined from its aetiology

Generally speaking, macrocytosis affects the kidneys because the enlarged cells sort of "clog" up the tubes so to speak inside the kidneys!. Depending on the severity of the macrocytosis, it can be treated with B-12 supplements or injections!. If you have further questions feel free to contact me!.Www@Answer-Health@Com

The only macrocytosis I know of is macrocytic anemia!. In that context it means the red cells are bigger than normal!. It is most commonly caused by a deficiency in Vit B12 or folic acid!. Anemia means that there is not enough useful hemoglobin and hematocrit!. Hemoglobin is the stuff in blood cells carrying around the oxygen and hematocrit is the percentage of cells in the blood!. I don't know of direct links between macrocytosis and kidneys, but some drugs given after kidney transplant can cause it!. Most causes are very treatable!. Hope that helps a little- make sure you talk more with his doctor and clarify!.Www@Answer-Health@Com





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