If a man has hemophilia, his sons cannot inherit the disease from him, but his d!
Question: If a man has hemophilia, his sons cannot inherit the disease from him, but his daughters can!. Why!?!?
If a man has hemophilia, his sons cannot inherit the disease from him, but his daughters can!. Why!? Please explain with references!.Www@Answer-Health@Com
Answers:
Because the hemophilia gene is passed on via the X chromosome!. If a child is a boy his sex chromosomes are XY!. He gets the X from his mother and the Y from his father!. So the father's defective X chromosome is not passed to his sons!. If a child is a girl she has the sex chromosomes XX (one from her father and one from her mother), so the defective X chromosome is passed from father to daughter!.
The daughter is then a "carrier" as one of her 2 X chromosomes carries the hemophilia gene!. Her non-defective X chromosome stops her from actually showing signs of the disease!. Her sons have a 50% chance of inheriting the disease (depending on whether she passes her normal X or her faulty X chromosome onto them!.
A "normal" X chromosome is strong enough to stop hemophilia from showing in women, even if they also carry a defective X, but the Y chromosome in men is not able to cancel out the effects of a defective X!.
http://www!.accessexcellence!.org/RC/VL/GG!.!.!.Www@Answer-Health@Com
The daughter is then a "carrier" as one of her 2 X chromosomes carries the hemophilia gene!. Her non-defective X chromosome stops her from actually showing signs of the disease!. Her sons have a 50% chance of inheriting the disease (depending on whether she passes her normal X or her faulty X chromosome onto them!.
A "normal" X chromosome is strong enough to stop hemophilia from showing in women, even if they also carry a defective X, but the Y chromosome in men is not able to cancel out the effects of a defective X!.
http://www!.accessexcellence!.org/RC/VL/GG!.!.!.Www@Answer-Health@Com
if you donate your y instead of your x chromosome, knowing that a female can only give an x, then he cannot have it because you didn't give him the infected x chromosome!. genetic disorders such as hemophilia can only be carried on an x chromosome!. if you give the infected x that you have down to your offspring, which knowing that you wife can only give an x chromosome makes that offspring a girl, there IS a chance she can get it because you passed down the only thing in your xy makeup that can cause it, which is an x!.
hopefully i didnt confuse you on this!.Www@Answer-Health@Com
hopefully i didnt confuse you on this!.Www@Answer-Health@Com
A woman can get homophilia, its just EXTREMELY rare!. Its a genetic disorder!. For a woman to get it, thier father must be affected by it, and thier mother must be a carrier of it!. Men have 1 Y chromosome and 1 X chromosome!. The X chromosome is affected by this disorder, and since he doen't have a back up, it destroys the factor for clotting!. Females on the other hand have 2 X chromosomes!. So if only 1 is affected by this, the other will take over, so they are not affected by this disorder!. But if each parent passes on the gene for it, she will be affected!.
I had to read the explanation several times to understand it, so i simplified it for you as much as i could!. if you want to see the whole explanation as i saw it, go to my source list!.
-meWww@Answer-Health@Com
I had to read the explanation several times to understand it, so i simplified it for you as much as i could!. if you want to see the whole explanation as i saw it, go to my source list!.
-meWww@Answer-Health@Com