What is Huntington's disease?!
Question: What is Huntington's disease!?
Answers:
Huntington's disease, also called Huntington's chorea, chorea major, or HD, is a genetic neurological disorder inherited by approximately 3 to 7 per 100,000 people of Western European descent, varying geographically, down to 1 per 1,000,000 of Asian and African descent!.[1] The name is derived from the physician George Huntington who described it precisely in 1872!. The disorder has been heavily researched in the last few decades, and it was one of the first inherited genetic disorders for which an accurate test could be performed!.
Huntington's disease's most obvious symptoms are abnormal body movements called chorea and a lack of coordination, but it also affects a number of mental abilities and some aspects of behavior!. Physical symptoms occur in a large range of ages around a mean occurrence of late forties/early fifties, but if they occur before the age of 20 then the condition is known as Juvenile HD!. As there is currently no proven cure, symptoms are managed with various medications and supportive services!.
Huntington's disease is one of several polyglutamine diseases caused by a trinucleotide repeat expansion!. This expansion is in the Huntingtin gene, which codes for Huntingtin protein (Htt), producing mutant Huntingtin (mHtt)!. The misfunction of this protein increases mitochondrial dysfunction and neuronal cell death in select areas of the brain as the normal age-related decline in general brain cell function means that the cells eventually can no longer handle the mutant protein, usually at around 40-50 years of age!. This damage itself isn't fatal, but life expectancy is reduced due to complications caused by its symptoms!.Www@Answer-Health@Com
Huntington's disease's most obvious symptoms are abnormal body movements called chorea and a lack of coordination, but it also affects a number of mental abilities and some aspects of behavior!. Physical symptoms occur in a large range of ages around a mean occurrence of late forties/early fifties, but if they occur before the age of 20 then the condition is known as Juvenile HD!. As there is currently no proven cure, symptoms are managed with various medications and supportive services!.
Huntington's disease is one of several polyglutamine diseases caused by a trinucleotide repeat expansion!. This expansion is in the Huntingtin gene, which codes for Huntingtin protein (Htt), producing mutant Huntingtin (mHtt)!. The misfunction of this protein increases mitochondrial dysfunction and neuronal cell death in select areas of the brain as the normal age-related decline in general brain cell function means that the cells eventually can no longer handle the mutant protein, usually at around 40-50 years of age!. This damage itself isn't fatal, but life expectancy is reduced due to complications caused by its symptoms!.Www@Answer-Health@Com
Huntington's disease (HD) results from genetically programmed degeneration of brain cells, called neurons, in certain areas of the brain!. This degeneration causes uncontrolled movements, loss of intellectual faculties, and emotional disturbance!. HD is a familial disease, passed from parent to child through a mutation in the normal gene!.Www@Answer-Health@Com
http://en!.wikipedia!.org/wiki/Huntington_!.!.!.
It is a neurological disease that could shorten a person's life span!. Usual symptoms appear when a person is older, and could range from stiffness to random muscle delayed!. It targets specific cells and destroys them!.Www@Answer-Health@Com
It is a neurological disease that could shorten a person's life span!. Usual symptoms appear when a person is older, and could range from stiffness to random muscle delayed!. It targets specific cells and destroys them!.Www@Answer-Health@Com
I'm pretty sure it is a disease that involves the breakdown of areas of the brain!. It usually doesn't start until 40 or 50 years of age!. That's pretty much all I know though!. Sorry!.Www@Answer-Health@Com
It's a genetic disease that is late acting!.!. it usually hits around mid 40's!. It is characterized by mood swings, irritability, memory loss, etc!.!.Www@Answer-Health@Com