How can I get rid of Granuloma Anulaire????!


Question: How can I get rid of Granuloma Anulaire!?!?!?!?
It's a skin condition that is itchy sometimes, but not always!. It starts out like little raised red circles on the skin and apparently it's common in diabetics!. Has anyone ever connected the medication "Metformin" with the skin rash!?Www@Answer-Health@Com


Answers:
Stressed1,
The etiology of granuloma annulare remains unknown!. Therefore your question referencing the drug metformin hydrochloride, which is used to help control blood sugar levels in people with type 2 or non-insulin dependent diabetes, I regret, is not answerable!. You may well be aware of most of the following details, but I shall put them here in case you are not conversant with all of them!. Granuloma annulare (GA) is a benign self-limited dermatosis characterized by a raised annular configuration!. It may be localized, generalized, perforating, or subcutaneous!. Lesions of the first 3 presentations have similar appearances, but each one follows a distinctive clinical course!. Subcutaneous GA appears differently, as it is a disease of childhood in which deep dermal or subcutaneous nodules lie on or near the periosteum and are distributed on the feet, lower legs, fingers, hands, forearms, scalp, and forehead!. GA is a self-limited cosmetic disease without any systemic medical complications!. On rare occasions, it may involve fascia and tendons and may cause sclerosis, lymphedema, and deformities such as joint ankylosis!. GA has been epidemiologically linked to diabetes mellitus, necrobiosis lipoidica diabeticorum, and rheumatoid nodules!. In GA, females are slightly more affected than males!. Pre-hospital care is not a consideration for patients with GA, which is a nuisance lesion!. Localized GA is not often symptomatic and it has a tendency towards spontaneous resolution!. Reassurance is often all that is necessary!. Painful or disfiguring lesions have been treated by various methods, although the level of evidence supporting these methods is low!. Localized lesions have been treated with potent topical corticosteroids with or without occlusion for 4-6 weeks, as well as with intralesional corticosteroids with varying total doses of steroid!. Cryotherapy using liquid nitrogen or nitrous oxide as refrigerants has been shown in a prospective, uncontrolled trial to be an effective treatment for localized GA!. Secondary dyschromia may be a complication of cryotherapy!. Other anecdotes of therapeutic efficacy in both localized and generalized GA involve tacrolimus and pimecrolimus!. Generalized GA tends to be more persistent and unsightly!. Treatment of the generalized disease is unfortunately fraught with a lack of consistently effective options!. While the treatment of choice remains to be defined, the available literature supports the use of isotretinoin or phototherapy with oral psoralen and UV-A (PUVA) as first-line options for generalized GA!. Other anecdotal reports and small series describe successful treatment with dapsone, systemic steroids, pentoxifylline, hydroxychloroquine, cyclosporine, fumaric esters, interferon-gamma, potassium iodide, and nicotinamide!.

The information provided here should not be used during any medical emergency or for the diagnosis or treatment of any medical condition!. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions!.
I add a link with details of this subject

http://www!.patient!.co!.uk/
showdoc/40024967/


Hope this helps
matador 89Www@Answer-Health@Com





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