Polio Vaccine--what kind of immunity will develop??!
Question: Polio Vaccine--what kind of immunity will develop!?!?
Answers:
The polio vaccine generates what is called adaptive immunity (rather than inherent)!.
The adaptive immunity is a function of lymphocytes!. Because polio is a DNA based virus, immunization results in immunological memory!. This is where immune cells that recognize a polio antigen "go to sleep" and live for many years with the sole purpose of waking up and being a key starter cell to fight off a future infection!.
I hope this answers your question!.Www@Answer-Health@Com
The adaptive immunity is a function of lymphocytes!. Because polio is a DNA based virus, immunization results in immunological memory!. This is where immune cells that recognize a polio antigen "go to sleep" and live for many years with the sole purpose of waking up and being a key starter cell to fight off a future infection!.
I hope this answers your question!.Www@Answer-Health@Com
Answers:
Polio vaccination works by priming the immune system with an 'immunogen'!. Stimulating immune response, via use of an infectious agent, is known as immunization!. Vaccine efficacy is defined by the amount of immunity against infection a particular vaccine provides, and is often measured by detection of protective antibodies in the blood!.
The development of immunity to polio efficiently blocks person-to-person transmission of wild poliovirus, thereby protecting both individual vaccine recipients and the wider community!. Because there is no long term carrier state for poliovirus in immunocompetent individuals, polioviruses have no non-primate reservoir in nature, and survival of the virus in the environment for an extended period of times appears to be remote, interruption of person-to person transmission of the virus by vaccination is the critical step in global polio eradication!.
After two doses of inactivated polio vaccine (IPV), ninety percent or more of individuals develop protective antibody to all three serotypes of poliovirus, and at least 99% are immune to poliovirus following three doses!. A single dose of oral polio vaccince produces immunity to all three poliovirus serotypes in approximately 50% of recipients!.Three doses of live-attenuated OPV produce protective antibody to all three poliovirus types in more than 95% of recipients!. OPV produces excellent immunity in the intestine, the primary site of wild poliovirus entry, which helps prevent infection with wild virus in areas where the virus is endemic!. IPV produces less gastrointestinal immunity than does OPV, so persons who receive IPV are more easily infected with wild poliovirus!. In regions without wild poliovirus, inactivated polio vaccine is the vaccine of choice!.[30] In regions with higher incidence of polio, and thus a different relative risk between efficacy and reversion of the vaccine to a virulent form, live vaccine is still used!. The live virus also has stringent requirements for transport and storage, which are a problem in some hot or remote areas!.
As with other live-virus vaccines, immunity initiated by OPV is probably lifelong!. The duration of immunity induced by IPV is not known with certainty, although a complete series is thought to provide protection for many years!.
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I have taken this answer from another site!. It is mostly correct, yet it does not tell you that the OPV contains a small amount of the live polio virus and can cause polio! This is part of the reason that the children in the third world countries are still getting polio!. There is about a three day window (I believe it is) that the can become infected with polio and pass it on to someone in the same manner we can pass a cold to another person!. Polio is a virus, a very dangerous one!. You get an immunization against the current flu bugs by them gathering up last years virus's and immunizing you against them!. This is the same thing that happens with the polio vaccine!. The shot helps your body recognize it and sets it to fight it, thus we become immune to polio!. But unfortunately not in all cases with the OPV!.
Fiksdal, President
International Post Polio Support Organization (IPPSO)
http://www!.ippso-world!.orgWww@Answer-Health@Com
Polio vaccination works by priming the immune system with an 'immunogen'!. Stimulating immune response, via use of an infectious agent, is known as immunization!. Vaccine efficacy is defined by the amount of immunity against infection a particular vaccine provides, and is often measured by detection of protective antibodies in the blood!.
The development of immunity to polio efficiently blocks person-to-person transmission of wild poliovirus, thereby protecting both individual vaccine recipients and the wider community!. Because there is no long term carrier state for poliovirus in immunocompetent individuals, polioviruses have no non-primate reservoir in nature, and survival of the virus in the environment for an extended period of times appears to be remote, interruption of person-to person transmission of the virus by vaccination is the critical step in global polio eradication!.
After two doses of inactivated polio vaccine (IPV), ninety percent or more of individuals develop protective antibody to all three serotypes of poliovirus, and at least 99% are immune to poliovirus following three doses!. A single dose of oral polio vaccince produces immunity to all three poliovirus serotypes in approximately 50% of recipients!.Three doses of live-attenuated OPV produce protective antibody to all three poliovirus types in more than 95% of recipients!. OPV produces excellent immunity in the intestine, the primary site of wild poliovirus entry, which helps prevent infection with wild virus in areas where the virus is endemic!. IPV produces less gastrointestinal immunity than does OPV, so persons who receive IPV are more easily infected with wild poliovirus!. In regions without wild poliovirus, inactivated polio vaccine is the vaccine of choice!.[30] In regions with higher incidence of polio, and thus a different relative risk between efficacy and reversion of the vaccine to a virulent form, live vaccine is still used!. The live virus also has stringent requirements for transport and storage, which are a problem in some hot or remote areas!.
As with other live-virus vaccines, immunity initiated by OPV is probably lifelong!. The duration of immunity induced by IPV is not known with certainty, although a complete series is thought to provide protection for many years!.
--------------------------------------!.!.!.
I have taken this answer from another site!. It is mostly correct, yet it does not tell you that the OPV contains a small amount of the live polio virus and can cause polio! This is part of the reason that the children in the third world countries are still getting polio!. There is about a three day window (I believe it is) that the can become infected with polio and pass it on to someone in the same manner we can pass a cold to another person!. Polio is a virus, a very dangerous one!. You get an immunization against the current flu bugs by them gathering up last years virus's and immunizing you against them!. This is the same thing that happens with the polio vaccine!. The shot helps your body recognize it and sets it to fight it, thus we become immune to polio!. But unfortunately not in all cases with the OPV!.
Fiksdal, President
International Post Polio Support Organization (IPPSO)
http://www!.ippso-world!.orgWww@Answer-Health@Com