I'm just curious to know how many people out there know what klinefelter syn!
Question: I'm just curious to know how many people out there know what klinefelter syndrome is!?
because my brother has it, and i feel like many people don't know what it is!.Www@Answer-Health@Com
Answers:
I am familiar with it, but I am a nurse!.
A lot of people don't know what it is, it is not common and not something you hear about often!. Www@Answer-Health@Com
A lot of people don't know what it is, it is not common and not something you hear about often!. Www@Answer-Health@Com
Klinefelter's syndrome, 47,XXY or XXY syndrome is a condition caused by a chromosome aneuploidy!. Affected individuals have at least two X chromosomes and at least one Y chromosome!.[1]
The principal effects are development of small testicles and reduced fertility!. A variety of other physical and behavioral differences and problems are common, though severity varies and many boys and men with the condition have few detectable symptoms!.
The extra X chromosome is retained because of a nondisjunction event during meiosis (sex cell division)!. The XXY chromosome arrangement is one of the most common genetic variations from the XY karyotype, occurring in about 1 in 500 live male births!.[3]
In mammals with more than one X chromosome, the genes on all but one X chromosome are not expressed; this is known as X inactivation!. This happens in XXY males as well as normal XX females!.[13] A few genes located in the pseudoautosomal regions, however, have corresponding genes on the Y chromosome and are capable of being expressed!.[14] These triploid genes in XXY males may be responsible for symptoms associated with Klinefelter's syndrome!.
Treatment
The genetic variation is irreversible, but its symptoms can be altered or treated in a number of ways, including the use of testosterone treatment!.
Inadequately treated hypogonadism in Klinefelter syndrome increases recognized psychosocial morbidity!.At least one study indicates that planned and timed support should be provided for young men with Klinefelter syndrome, to ameliorate current poor psychosocial outcomes!.Www@Answer-Health@Com
The principal effects are development of small testicles and reduced fertility!. A variety of other physical and behavioral differences and problems are common, though severity varies and many boys and men with the condition have few detectable symptoms!.
The extra X chromosome is retained because of a nondisjunction event during meiosis (sex cell division)!. The XXY chromosome arrangement is one of the most common genetic variations from the XY karyotype, occurring in about 1 in 500 live male births!.[3]
In mammals with more than one X chromosome, the genes on all but one X chromosome are not expressed; this is known as X inactivation!. This happens in XXY males as well as normal XX females!.[13] A few genes located in the pseudoautosomal regions, however, have corresponding genes on the Y chromosome and are capable of being expressed!.[14] These triploid genes in XXY males may be responsible for symptoms associated with Klinefelter's syndrome!.
Treatment
The genetic variation is irreversible, but its symptoms can be altered or treated in a number of ways, including the use of testosterone treatment!.
Inadequately treated hypogonadism in Klinefelter syndrome increases recognized psychosocial morbidity!.At least one study indicates that planned and timed support should be provided for young men with Klinefelter syndrome, to ameliorate current poor psychosocial outcomes!.Www@Answer-Health@Com