My boyfriend has cystic fibrosis if you have a lung transplanted does the cf dis!


Question:

My boyfriend has cystic fibrosis if you have a lung transplanted does the cf disease infect the new lung?

He is actually doing really well. But of course I always worry. But I have read a couple of sites that say if you recieve a new lung then that lung will not have the cf disease. please help!

Additional Details

4 days ago
Thank you to everyone who has answered my question!! He is 22 and is doing really good. One more question though. Anyone who has or had CF is there any tricks you guys have to bringing more up in treatments or any special things that you all have done to keep extra healthy?


Answers:

Important distinction here: Single lung transplant -> Native lung will still have CF; new lung will not. However, the bacteria living in the native (affected) lung will spread to the transplanted lung, and the transplant recipient is immunosuppressed, so the pre-existing bacteria will cause infection and death. Hence, single lung transplants are NOT done for CF patients. Double lung transplant -> new lungs will NOT have CF or bacteria, but getting a transplant carries a high risk of short-term mortality (due to the trauma of getting your lungs "ripped" out & the risk of a sudden rejection of the donor lungs) and the immunosuppression still makes the recipient susceptible to infections from outside his body. Plus, no drug is without side effects and immunosuppressants can be directly toxic to organs like the kidneys. Moreover, despite best medical practices--even in patients who survive repeated infections & drug-toxicities--the new lungs get rejected by the recipient over the course of years and then the recipient either needs a new transplant (unlikely, BTW) or dies. Furthermore (especially because of immunosuppression) there are also small risks of acquiring a cancer from the donor lungs themselves (or independently) or an infection from imperfect sterility during (or surrounding) the operation. Lastly, even a double lung transplant doesn't cure all symptoms of CF; there's still liver disease (the second leading cause of death among patients with CF) & many of the health risks associated with diabetes with which CF patients must contend. BTW: Steroids in particular (one family of immunosuppressive drugs) tend to raise blood sugar, making for terrible diabetes control. Bottom-line: *Double lung* transplantation can be a life-extending measure for CF patients with a relatively short projected life expectancy, but obtaining a transplant is by no means guaranteed even if a patient wants and is eligible for one, the procedure and its consequences are not without major risks, and it's not in *any* sense a cure. As for your boyfriend's specific risk-benefit ratio for transplantation--that's something he should discuss with his CF specialist physician. In general, the best course of action for any CF patient's health is to be as close to 100% compliant with his doctor's advice as is possible. Good luck to you and your boyfriend!




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