Does anyone have an idea what a lymphoplasmacytoma is?!


Question:

Does anyone have an idea what a lymphoplasmacytoma is?

Is it a type of lymphoma or plasmacytoma? thanks


Answers:

Plasmacytoma is a localized collection of monoclonal plasma cells. The disease is divided into primary plasmacytoma of the bone and extramedullary plasmacytoma. The importance of the diagnosis rests with the potential for these disorders to progress to multiple myeloma. Solitary plasmacytoma of the bone are usually painful and present with a lytic lesion on radiographs. By definition, the bone lesion can be diagnosed if there is:

Single bone lesion with histology consistent with a plasma cell tumor
Absence of a plasma cell infiltrate in random bone marrow biopsies
No evidence of other bone lesions by radiographic examination
Absence of renal failure
No hypercalcemia
No anemia




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