Why is Parkinson's disease a genetic disorder?!


Question: Why is Parkinson's disease a genetic disorder?
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First of all, PD is not considered to be only a genetic disease. At this time only about 15-20% of the cases are thought to be genetic in origin. The remaining 80-85% are considered idiopathic. In most cases environmental triggers are thought to be responsible for initializing the disease process whereby dopamine neurotransmitter neurons in the substantia nigra die and their loss triggers a loss of norepinephrine neurons and somehow a serotonin loss.

There are now several genes which have been identified with mutations which are responsible for Parkinson's disease which appears to be a collection of similar syndromes which cause motor and non-motion symptoms as well as psychological/cognition problems.

You can read more about the genes at the sites linked below:
http://www.ncbi.nlm.nih.gov/books/NBK122…
http://ghr.nlm.nih.gov/condition/parkins…
http://datam.i2r.a-star.edu.sg/mdpd/
http://www.sciencedaily.com/releases/200…

Parkinson's disease has been called many things throughout the thousands of years it has been known and treated. At this time there appears to be growing evidence pointing to genetics but there is much research waiting to be conducted and completed.

http://parkinsonsfocustoday.blogspot.com…



the effect of it is still unknown more research is needed however they think if they can figure out the eviormental cause of the disease they can get the genes to stop reproducing causing p.d.

hope this helped



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