I picked up 50 pounds in 3 months!!! Why cant I loose it again?!

I picked up 50 pounds in 3 months!!! Why cant I loose it again?

Through healthy eating, exercise, etc. I managed to loose 65 pounds, maintained for 1 year. Got married Dec 06, moved to the USA 12 Jan this year and from then till middle April gained 55 pounds!!! Yes, I did indulge in EVERYTHING unhealthy, fattening, etc! I have since about 20 April gone back to healthy eating, exercing but only managed to loose 1.5 pounds and 15m overall!!! Have I messed up my metabolism, why can I not loose weight! I am trying so hard and are really depressed at this stage, I HATE myself and had to buy new clothes as nothing fits me! I accept that it is all my fault but I cannot understand why I cannot loose again?? I should still be on honeymoon but are so depressed coz I HATE the way I look? My marriage is suffering! I am 42 yrs of age... I spend 2- 2,5 hrs in the gym 5 days a week, (1 hr cardio, then weight training) eat 5 small meals, drink lots of water. What have I done??? Is there hope? Should I try Alli, will this help me? Anyone had success with it?

see a doctor, maybe there is a medical reason