Does it make sense for a doctor to up your dosage a huge amount?!


Question: I am bi-polar and I have called my doctor three times. They never called back. That said, I was taking bupropion (Wellbutrin) a total of 200mg daily. I also take lithium three times a day 900mg I believe. I went back to the doctor this past Tuesday and she increased my bupropion to 400mg. Its extended release. The reason I'm annoyed is because I am nauseous all day. I felt bad after the first day I had the full dose. I've been all over WebMD but it only says half the medicine in America could cause you to be nauseous. So, was this jump in mg to blame? And is this too much bupropion to be on? I thought the highest dose was 350mg?


Answers: I am bi-polar and I have called my doctor three times. They never called back. That said, I was taking bupropion (Wellbutrin) a total of 200mg daily. I also take lithium three times a day 900mg I believe. I went back to the doctor this past Tuesday and she increased my bupropion to 400mg. Its extended release. The reason I'm annoyed is because I am nauseous all day. I felt bad after the first day I had the full dose. I've been all over WebMD but it only says half the medicine in America could cause you to be nauseous. So, was this jump in mg to blame? And is this too much bupropion to be on? I thought the highest dose was 350mg?

Sweetie, Call the Pharmacist immediately. They are SO kind, smart, and helpful, and meds are their "thing!" The pharmacist will guide you. I promise! Tell him/her exactly what you wrote in your question.

If your pharmacist is closed now, look up "Pharmacies" in the Yellow Pages. Find an ad for a 24-hour pharmacy.

Bless you and good luck! :)

Sounds like you need to talk to your Dr. again. This time make an appointment. They have so many patients they don't really know who you are unless they see you and have your chart in front of them.

300mg per day is the average dosage someone recieves but dosages have been known to go as high as 600mg. Any dosage that exceeds 450mg per day starts to become dangerous as it increases your chances of having a seizure.

The nausea you are suffering from is due to an increase in your increased bupropion med

Well, first of all...is the release of the Bupropion extended or sustained? It matters to whether or not the original prescription was written for Wellbutrin XL (extended release) or Wellbutrin SR (sustained release) as to what dosage is appropriate. Bupropion is the active ingredient in both Wellbutrin XL and Wellbutrin SR.

Wellbutrin XL comes in two strengths: 150mg and 300mg. Wellbutrin XL is a once daily dose. Taking more than 450mg a day increases the chance of serious side effects.

Wellbutrin SR comes in three strengths: 100mg, 150mg, and 200mg. The recommended maximum daily dose of Wellbutrin SR is 400mg, taken in TWO doses of 200mg each.

It seems that you are taking Bupropion HCL in the sustained release formula since you said she doubled your dose from 200mg up to 400mg. If you had been taking Bupropion HCL in the extended release formula, you would have started out on 150mg and would have been doubled to 300mg.

Here are the complete prescribing guides for both:
http://us.gsk.com/products/assets/us_wel...
http://us.gsk.com/products/assets/us_wel...





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