Hello does anybody here suffer with hydrentis suppativa would like to meet other!


Question:

Hello does anybody here suffer with hydrentis suppativa would like to meet other with this?


Answers:

That's hidradenitis suppurativa.

Hidradenitis suppurativa is a chronic and often disabling disease characterized by intermittent periods of inflammation and abscess formation in sweat gland-containing skin.

Hidradenitis suppurativa (HS) is a chronic disease of unknown etiology that mainly affects the genitofemoral, perianal and axillary regions . The disease is believed to be follicular in origin. HS has a higher prevalence in women than men and is estimated to affect 4 percent of women in the general population.

HS often occurs in multiple members within families, suggesting a genetic predisposition. Various etiological agents have been associated. The increased incidence of HS in obese women with acne led to the theory of HS being associated with an hyperandrogenic endocrine disorder . Though the role of androgens in HS is still not clear. Smoking, lithium and oral contraceptives may also be associated with HS, possibly as triggering factors. Nonetheless, the etiology of the disease is unknown.

HS may arise singularly or multifocally in the genitofemoral, perianal and axillary areas. The lesions are painful and have a foul odor attributed to bacterial colonization. Erythematous dermal abscesses form that measure up to 2 cm in diameter. Untreated abscesses will gradually increase in size and may drain to the surface. The course of HS is chronic and remitting, with new abscesses arising in previously unaffected areas or in regions of past involvement. Scarring, fibrosis and sinus tract formations are manifestations of late disease. Strictures can occur secondary to sinus tracts; fistulas may also complicate HS.

The follicular occlusion triad consists of HS, acne conglobata and perifolliculitis capitis abscedens et suffodiens. Arthritis of peripheral joints and the axial skeletion may rarely be associated with HS. HS has also been linked to Crohn's disease . One study reported 24 out of 61 patients with HS were also diagnosed with Crohn's disease, which predated the HS by an average of 3.5 years.

Treatment of hidradenitis suppurativa is challenging. Late stage disease, evidenced by the formation of sinus tracts, fibrosis and scarring, usually necessitates surgical intervention. Early HS is often best treated with antibiotics in our experience, although few clinical trials are available. Three months' of treatment with topical clindamycin decreased the number of abscesses, inflammatory nodules and pustules in twenty-seven patients with chronic HS. Systemic tetracycline therapy has shown similar clinical effectiveness. Others and also we often recommend intrealesional corticosteroids in early stage disease. The use of cyproterone acetate and ethinyl estradiol achieved successful clinical results in four women with chronic HS ; clinical improvement with cyproterone acetate and ethinyl estradiol was also described in another study. Isotretinoin is only slightly effective in controlling the disease; clinical improvement is seen in patients with mild HS. The clearing of chronic, refractory perianal HS was seen after treatment with cyclosporin for concomitant pyoderma gangrenosum.
Medical therapy is of limited value once HS has progressed past its early stage. The surgical option of choice for late stage HS is wide local excision with healing by secondary intention. More recently, carbon dioxide laser excision has been proposed as a better alternative to conventional surgery. Carbon dioxide laser excision offers better hemostasis and visualization of abscessed tissue than conventional surgical techniques, allowing more accurate excision.




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