Oxycodone and itching?!


Question:

Oxycodone and itching?

im taking oxycodone which iv taken before with no problem but this time i was itching like crazy, and had a few hives, is that ok?


Answers:

As a pharmacist I get this question pretty often. Itching from oxycodone has two different, usually unrelated causes.

First is that you're allergic to narcotic pain relievers. This is actually fairly rare and you would see this reaction with nearly all narcotic pain releivers. This is particularly worrisome if you have difficulty breathing due to swelling of the throat or tongue.

Second, and much more common, is that this is a side-effect of oxycodone. This drug is known to commonly cause a release of histamine which causes the itching that you are experiencing.

In either case this can be treated with diphenhydramine (Benadryl).




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