Seroquel and Wellbutrin during pregnancy?!

Please call motherisk RIGHT NOW, they are only open another two hours today and then not until Monday!. They are the best!.

I will look into it a bit for you but I really think motherisk is your best option as they have all the current information and can take into consideration dosage, gestational age, etc!. I would not wait until Tuesday!.


You can call from anywhere you just pay the long distance!. Mon-Fri 9-5 EST
(416) 813-6780
motherisk!.com



First Unisom is considered safe to take during pregnancy!. It is used frequently for severe morning sickness!. However it is actually a sleep aid!. That may be appropriate in your sitation!.
http://www!.motherisk!.org/women/forum_que!.!.!.


http://www!.aafp!.org/afp/20020615/2507!.ht!.!.!.
Anti-anxiety, sleep B Buspirone (BuSpar), diphenhydramine (Benadryl), zolpidem (Ambien)
C Hydroxyzine (Atarax)
D Most benzodiazepines
X Flurazepam (Dalmane), temazepam (Restoril)

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Seroquel

http://safefetus!.com/DrugDetail!.asp!?Drug!.!.!.
Fetal Risk



* Carcinogenic in animals increasing the incidence of mammary adenocarcinomas in females and thyroid follicular cell benign adenomas in males!.
* By increasing serum prolactin level it impairs fertility and reduces pregnancy rate (in animal studies)!.
* Not teratogenic in animals but fetotoxic causing reduced fetal body weight, delayed skeletal ossification!.
* High doses in animals cause reduced weight gain, increased maternal, fetal and postnatal deaths!.
* No adequate human data!.


(sorry that's the only good source I can find)

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Wellbutrin

http://safefetus!.com/DrugDetail!.asp!?Drug!.!.!.
Fetal Risk



* An increase in congenital defects was reported without fetotoxicity in animals!.
* Limited human data has been reported, its use in the 1st trimester was documented to be without teratogenic effects!.

http://www!.ncbi!.nlm!.nih!.gov/pubmed/15746!.!.!.
CONCLUSION: These results suggest that bupropion does not increase the rates of major malformation above baseline!. The higher rates of spontaneous abortions are similar to other studies examining the safety of antidepressants during pregnancy!.

http://www!.healthyontario!.com/DrugDetail!.!.!.
Pregnancy: The safety of bupropion during pregnancy has not been established!. It has been reported that babies born to pregnant women who have taken medications of this kind during the last trimester of pregnancy may be adversely affected!. Physicians and pregnant women should carefully consider the benefits and the risks of all treatment options!.

http://www!.aafp!.org/afp/20020615/2507!.ht!.!.!.
Antidepressants B Bupropion (Wellbutrin)
C Desipramine (Norpramin), doxepin (Sinequan), mirtazapine (Remeron), nefazodone (Serzone), SSRIs, trazodone (Desyrel), venlafaxine (Effexor)
D Amitriptyline (Elavil), imipramine (Tofranil), nortriptyline (Pamelor)


http://www!.aafp!.org/afp/20020815/629!.htm!.!.!.
Risks of Specific Agents

ANTIDEPRESSANTS

The results of numerous studies that included thousands of pooled patients taking tricyclic antidepressants (TCAs) and the selective serotonin reuptake inhibitor (SSRI) fluoxetine (Prozac) support the relative safety of these medications for use throughout pregnancy!.8,17,18 Neither the TCAs nor fluoxetine has been associated with major teratogenic effects!.8,17,18 In addition, a well-designed follow-up study revealed no evidence of behavioral teratogenicity with these agents after up to seven years of follow-up!.19 There have been case reports of perinatal syndromes relating to all of these agents, but the effects appear to be mild, transient, and of questionable causation (Table 1)!.3,8-10
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Mood stabilizing agents such as lithium, valproic acid, and carbamazepine are known teratogens!.
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Fewer data are available about other widely used SSRIs!.18,20 Paroxetine (Paxil), sertraline (Zoloft), and citalopram (Celexa) have been studied prospectively in a few hundred women exposed at various times during pregnancy; these agents do not appear to increase the risk of teratogenesis!.18,20 Even fewer data are available about novel agents such as venlafaxine (Effexor), nefazodone (Serzone), or bupropion (Wellbutrin)!.3 Limited data on the use of monoamine oxidase inhibitors are not reassuring, and use of these agents is not recommended during pregnancy!.3




http://www!.obfocus!.com/high-risk/smoking!.!.!.
When counseling, cognitive and behavioral therapy are not successful, the use of pharmacotherapy, Bupropion (Wellbutrin, pregnancy category B) or Nicotine replacement products should be considered [8]


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St John's Wort

http://www!.otispregnancy!.org/pdf/stjohns!.!.!.
Can taking St!. John

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