Is it possible for some women to not be able to have an orgasm?!

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I think lots of women have trouble but I don't think there's a physical problem that causes it. It's either that the button isn't getting clicked right or she is tense or something.

Yes. A small number will NEVER have one.

Most often than not, however, many just won't experience them until their late teens or early 20s, and most of us only can achieve an orgasm through clitoral stimulation, not penetration.

depends, are you asking about intercourse, masturbation, or both?

Yes, if they are not stimulated during sex. Men are more likely to get orgasms.