Which is better for HRT PREMPRO or COMBIPATCH?!
Question:
Which is better for HRT PREMPRO or COMBIPATCH?
I switch my hormon replacment terapy from Prempro to a Combipatch (Estalis) by NOVARTIS , Is anyone uot there with any suggestion or experience any side effects?
Thank you.
Pina
Answers:
Both contains hormones estrogen and progesterone in different forms. Which is better depends on your personal preference.
Premarin is a oral form that requires daily intake. So, you need to take that every day. If you don't mind taking medication on daily basis and does not get much side effect from taking it, it's a good choice. There is some controversies with the estrogen form used in Prempro - it uses Premarin, which has some studies suggesting possibly increasing heart disease and breast cancer. That does not mean the other forms (including Estrodiol used in Combivent) does not have the same risk, but there are some possibility for sure with Premarin.
Combivent uses Eestrodiol, which some physicians prefer due to the studies (or lack of studies). The main advantage is that it is applied monthly. However, it is a skin application, and the patch sometimes can cause skin irritation after long time of application.