What does huntington's disease do to your apperance?!
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"Huntington's disease is a genetic, progressive, neurodegenerative disorder characterized by the gradual development of involuntary muscle movements affecting the hands, feet, face, and trunk and progressive deterioration of cognitive processes and memory (dementia). Neurologic movement abnormalities may include uncontrolled, irregular, rapid, jerky movements (chorea) and athetosis, a condition characterized by relatively slow, writhing involuntary movements."
My impression is that your basic physical appearance is relatively unchanged but that the person's involuntary movements are highly visible and would affect how others perceive them.