What is the safest anti depressant for a hypertensive patient on beta blockers a!
Question:
What is the safest anti depressant for a hypertensive patient on beta blockers and calcium channel blockers?
Answers:
Most commonly used antidepressants interact with beta blockers and calcium channel blockers to greater or lesser degrees through the CYP 3A4 system, generally resulting in intensified levels and effects of both, and possibly resulting in toxicity. That said, it's rarely a major clinical problem if doses are started low and heart rate / blood pressure is monitored; if the doses of the antihypertensive agents need to be decreased, they can be.