What's a antihistamine? (sp?)?!


Question:

What's a antihistamine? (sp?)?

What is a antihistamine and what does it do?


Answers:

An antihistamine is a drug which serves to reduce or eliminate effects mediated by histamine, an endogenous chemical mediator released during allergic reactions, through action at the histamine receptor. Only agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines - other agents may have antihistaminergic action but are not true antihistamines.

Histamine is a biogenic amine involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.[1] New evidence also indicates that histamine plays a role in chemotaxis of white blood cells.




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